. 2022 Nov 1;12:18377. doi: 10.1038/s41598-022-21934-6

Table 7.

Results of multivariable analysis of models in premanifest compared to control participants and in manifest compared to control participants.

Multivariable analysis	Adverse events	Headache	Back pain
Premanifest vs control OR 95% CI	1.18 [0.76–1.84]	1.06 [0.65–1.73]	1.70 [0.87–3.32]
Manifest vs control OR 95% CI	0.87 [0.53–1.42]	0.55 [0.31–0.98]	1.69 [0.76–3.77]
HDGEC vs control OR 95% CI	1.046 [0.70–1.56]	0.832 [0.54–1.30]	1.70 [0.91–3.20]

Multivariable analysis

Adverse events

Headache

Back pain

N = 657

Premanifest vs control

95% CI

1.18

[0.76–1.84]

1.06

[0.65–1.73]

1.70

[0.87–3.32]

Manifest vs control

95% CI

0.87

[0.53–1.42]

0.55

[0.31–0.98]

1.69

[0.76–3.77]

HDGEC vs control

95% CI

1.046

[0.70–1.56]

0.832

[0.54–1.30]

1.70

[0.91–3.20]

HDGEC HD gene expansion carrier, OR Odd ratio.