Table 1.

Comparison of patients with and without high MPO-DNA complex levels in each SLEDAI-2K variable.

	MPO-DNA low (n = 20)	MPO-DNA high (n = 13)	P value
Organic brain syndrome (%)	1/20 (5.00)	0/13 (0.00)	1.00
Visual disturbance (%)	3/20 (15.00)	1/13 (7.69)	1.00
Cranial nerve disorder (%)	1/20 (5.00)	0/13 (0.00)	1.00
Lupus headache (%)	2/20 (10.00)	0/13 (0.00)	0.51
Vasculitis (%)	2/20 (5.00)	0/13 (0.00)	0.51
Arthritis (%)	10/20 (50.00)	5/13 (38.46)	0.72
Myositis (%)	1/20 (5.00)	5/13 (38.46)	0.025
Urinary casts (%)	5/20 (25.00)	2/13 (15.38)	0.68
Hematuria (%)	6/20 (30.00)	0/13 (0.00)	0.060
Proteinuria (%)	5/20 (25.00)	3/13 (23.08)	1.00
Pyuria (%)	3/20 (15.00)	1/13 (7.69)	1.00
Rash (%)	2/20 (10.00)	4/13 (30.77)	0.18
Alopecia (%)	2/20 (10.00)	1/13 (7.69)	1.00
Mucosal ulcers (%)	2/20 (10.00)	2/13 (15.38)	1.00
Pleurisy (%)	1/20 (5.00)	5/13 (38.46)	0.025
Pericarditis (%)	0/20 (0.00)	2/13 (15.38)	0.15
Low complement (%)	17/20 (85.00)	8/13 (61.54)	0.21
Increased anti-dsDNA Ab (%)	14/20 (70.00)	1/13 (7.69)	< 0.001
Fever (%)	5/20 (25.00)	5/13 (38.46)	0.46
Thrombocytopenia (%)	2/20 (10.00)	4/13 (30.77)	0.18
Leukopenia (%)	4/20 (20.00)	2/13 (15.38)	1.00
SLEDAI-2 K score (mean [SD])	13.95 (7.43)	9.92 (7.57)	0.14
CRP (mg/dL; median [IQR])	0.22 (0.033–0.35)	2.10 (0.49–8.37)	0.001
ESR (mm/h; mean [SD])	48.55 (30.25)	62.85 (34.04)	0.22

The MPO-DNA high group was defined as OD value > 0.62 (mean + 2SD of HC). Group differences in the proportion of categorical variables were analyzed using Fisher’s exact tests.

Anti-dsDNA Ab anti-double stranded DNA antibody, CRP C-reactive protein, ESR erythrocyte sedimentation rate, HC healthy control, MPO-DNA myeloperoxidase-DNA, OD optical density, SD standard deviation, SLEDAI-2K systemic lupus erythematosus disease activity index 2000.