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. 2022 Nov 1;20:149. doi: 10.1186/s43141-022-00431-3

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Distribution of major hotspot mutant genes in 405,461 global samples with complete SARS-CoV-2 genome sequences. Complete genomes sequences from National Center for Biotechnology Information (NCBI) database were analyzed for top mutant genes as of August 4th, 2021, a total of 405,461 complete SARS-CoV-2 genomes from 88 countries were analyzed