Table 3.
Individual cases of rapid eye movement sleep–related sinus arrest
| Year, ref. | Age, sex | PMH | Symptoms | Normal diurnal cardiac eval. | Abnormal diurnal cardiac eval. | Cardiac monitor, longest pause (s) | PSG, longest pause (s) | Device? |
|---|---|---|---|---|---|---|---|---|
| 198412 | 30, F | None | Syncope after awakening, CP, palpitations | ECG, EST, TTE, Cath, EPS, ANS | None | 9 | 5 | PPM |
| 198412 | 27, M | None | CP, dizziness | ECG, EST, Cath, ANS | None | 8 | 5 | PPM |
| 198412 | 35, M | None | Syncope after awakening, CP | ECG, EST, Cath, ANS | None | 7 | 6 | PPM |
| 198412 | NR, M | None | CP | ECG, EST, EPS, ANS | None | 8 | 6 | None |
| 199919 | 27, M | None | Syncope w/ nocturnal BMI, CP, dizziness | EST, TTE, EPS, Tilt, ANS | None | 7.2 | 5 | None |
| 200421 | 23, M | None | None | ECG, EST, TTE, Tilt, EPS | None | 11.8 | 5.5 | PPM |
| 200722 | 54, M | BMI 37 | CP, presyncope w/exercise | EST, TTE, ANS | None | 7.0 | 6.7 | PPM |
| 200722 | 41, M | None | CP | TTE, Cath, Tilt | None | 8.2 | 11 | PPM |
| 201113 | 29, M | None | Presyncope w/ exercise | ECG, Cath, EST | None | 12 | 10 | PPM |
| 201113 | 23, M | None | Presyncope w/ early AM urination | ECG, Cath, EST | None | 15 | 7 | PPM |
| 201113 | 20, F | None | Syncope w/menstruation | ECG, Cath | None | 11 | 8 | PPM |
| 201113 | 22, M | None | Unknown | ECG, Cath, EPS | None | 13 | 7 | PPM |
| 201113 | 24, M | None | Presyncope w/exercise | ECG, Cath, EPS | None | 12 | 10 | PPM |
| 201113 | 21, M | None | Presyncope w/intercourse | ECG, Cath, EPS | None | 14 | 6 | PPM |
| 201113 | 19, M | None | Malaise w/exercise | ECG, Cath, EPS | None | 12 | 5 | PPM |
| 201113 | 18, F | None | Malaise w/exercise | ECG, Cath, EPS | None | 12 | 10 | PPM |
| 201113 | 23, M | None | Presyncope after awakening | ECG, Cath, EPS | None | 9 | 9 | PPM |
| 201113 | 24, M | None | Presyncope w/exercise | ECG, Cath, EPS | None | 12 | 8 | PPM |
| 201214 | 43, M | None | None | None | Brady. on ECG | 13.8 | 5.1 | None |
| 201515 | 36, M | None | Syncope after awakening | ECG, TTE | EPS with pauses up to 4.1 s | 7.8 | 8.6 | PPM |
| 201816 | 49, M | BMI 34, HTN, pAF | Dyspnea, snoring | EST | TTE w/LVH, diastolic dys. | 5.5 | 5.5 | PPM |
| 202217 | 21, M | None | Presyncope after awakening | ECG, TTE, EST, EPS | None | 10.9 | 19.5 | PPM |
| Current | 63, M | Lyme (treated) | Syncope, presyncope w/exercise | ECG, TTE, EST | None | 12.1 | 6 | PPM |
ANS = autonomic nervous system study (eg, Valsalva ratio, heart rate variability); BMI = body mass index; Cath = cardiac catheterization (right- vs left-sided not specified); Brady. = bradycardia; CP = chest pain; dys = dysfunction; ECG = electrocardiogram; EPS = electrophysiology study; EST = exercise stress test; Eval. = evaluation; LVH = left ventricular hypertrophy; F = female; M = male; NR = not reported; pAF = paroxysmal atrial fibrillation; PMH = past medical history; PSG = polysomnography; Ref. = reference; Tilt = tilt table test; TTE = transthoracic echocardiogram.