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. 2022 Oct 19;13:965694. doi: 10.3389/fphar.2022.965694

TABLE 5.

Analysis of core regulatory targets in crucial active components

Inline graphicOverlapping Inline graphicQuercetin specific (Green) Inline graphicKaempferol specific (Blue) Inline graphicLuteolin specific (Yellow) Inline graphicWogonin specific (Red) Inline graphic7-O-methylisomucronulatol specific (orange)
AR ABCG2 F3 IRF1 PON1 ALOX5 CASP7 FN1 ADRB1
DPP4 ACP3 FOS MAOB PRKCA MAPK8 CDK4 KDR CCNA2
HSP90AA1 CASP8 GJA1 MMP3 RAF1 PGR IL4 ESR2
PPARG CAV1 HIF1A MPO RUNX2 SLC6A2 MDM2 HTR2A
PTGS1 CHEK2 HSPB1 MYC SERPINE1 SLPI MET PIM1
PTGS2 CRP IGF2 ODC1 SOD1 PCNA SLC6A4
CXCL10 IGFBP3 PARP1 SPP1 TYR
ELK1 IL1A PLAT TGFB1 XIAP
ERBB3 IL1B PLAU THBD

Targets identified as core regulatory targets were underlined and overstruck.