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. 2022 Oct 19;10:955127. doi: 10.3389/fbioe.2022.955127

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Copyright © 2022 Xu, Tan, Chen, Chen, Tang, Liao and Niu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The relative tumor growth curves and (B) photographs of tumors during the various treatments after 14 days. (C) The weight growth curves of different groups of mice after various treatments. (D) Microscopy images of TUNEL and PCNA assays of stained tumor tissues at different treatments: (Hussain and Nguyen, 2014) Saline, (Wells, 2006) US, (Wu et al., 2005) IR780/PLGA NPs, (Ahmadi et al., 2020) IR780/PLGA@MnO₂NPs, (Qian et al., 2016) IR780/PLGA NPs + US, (Wood and Sehgal, 2015) IR780/PLGA@MnO₂ NPs + US (scale bar, 200 µm). (E) The relative quantification of TUNEL and (F) PCNA after different treatments. (*p < 0.05).