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. 2022 Oct 19;9:1023511. doi: 10.3389/fmolb.2022.1023511

FIGURE 2.

FIGURE 2

Model for the function of ADAMTS6. ADAMTS6 locates and functions within the extracellular matrix and has been shown to cleave fibrillin-1, fibrillin-2, fibronectin, LTBP-1 and syndecan-4. It directly or indirectly effects cellular gap junctions as well as pericellular matrix/glycocalyx quantity.