TABLE 1.
Demographic characteristics of patients with AD and healthy controls
| Variables | AD (n = 159) | HCs (n = 299) | p Value |
|---|---|---|---|
| Demographics | |||
| Age, y, mean (SD) a | 63.03 (9.06) | 61.55 (8.92) | 0.093 |
| Sex, (m/f) b | 47/112 | 78/221 | 0.427 |
| Education, y, mean (SD) a | 9.24 (4.46) | 11.12 (4.55) | <0.001*** |
| Disease duration, mean (SD) | 2.76 (1.99) | NA | NA |
| Neuropsychological assessment, Mean (SD) | |||
| MMSE c | 15.14 (7.05) | 23.64 (3.59) | <0.001*** |
| MoCA | 10.04 (6.07) | NA | NA |
| CDR | 1.14 (0.81) | NA | NA |
| Ophthalmologic, Mean (SD) | |||
| IOP (mm Hg) a | 15.74 (2.76) | 15.37 (2.75) | 0.169 |
| BCVA a | 1.20 (0.25) | 1.21 (0.26) | 0.862 |
| AL a | 22.90 (0.93) | 23.02 (0.86) | 0.194 |
Abbreviations: AD, Alzheimer's disease; AL, axial length; BCVA, best‐corrected visual acuity; CDR, the global Clinical Dementia Rating; HCs, healthy controls; IOP, intraocular pressure; MMSE, Mini‐Mental State Examination; MoCA, Montreal Cognitive Assessment; SD, Standard deviation; y, years.
Note: Significant results in bold. *** p < 0.001.
a
Independent‐samples t‐test.
b
χ2 test.
c
Mann–Whitney U test.