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. 2022 Sep 20;28(12):1908–1920. doi: 10.1111/cns.13954

TABLE 1.

Differentiation markers of PVM and microglia

Markers Function PVM Microglia References
CD45 T cell and B cell receptor‐mediated activation ++ + [5]
CD11b Cell adhesion, apoptosis, chemotaxis + + [66, 67]
Cx3cr1 Fractalkine receptor + ++ [55, 68]
CSF1R Csf1 receptor + + [69, 70]
Iba‐1 Still unknown ++ + [51, 71]
F4/80 Interact with circulating immune cells ++ + [34, 72]
MHCII Antigen presentation ++ + [35, 54]
CD68 Lysosomal protein + +/− [73]
CD163 Endocytosis; scavenger receptor; antigen presentation + [61, 62, 74]
Lyve‐1 Hyaluronan receptor, controlling the expression of collagen in vascular smooth muscle cells + [75]
CD206 Mannose receptor; endocytosis + [5, 10, 40]
TMEM119 Still unknown + [41, 59, 60, 76]
P2RY12 Nucleotide receptor + [41, 77]
SALL1 A zinc‐finger transcription factor + [58]
CD169 Sialoadhesin, endocytosis + [78]
ANXA3 Belongs to the structurally‐related annexin protein family + [56]
Siglec‐H Still unknown + [57]