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. 2022 Oct 19;12:965660. doi: 10.3389/fonc.2022.965660

Figure 4.

Figure 4

CAFs’ conditioned medium (CM) promoted proliferation and migration of lung cancer cells after ionizing irradiation. (A) Representative images of wound healing assay for the A549 cells in irradiated group and unirradiated group treated with DMEM, CAF0-CM, and CAF8-CM; (B) Quantification of the change in healing area (%) over time in different subgroups; (C) Differences in the proliferation of A549 after irradiation with or without 6Gy in different conditioned medium were analyzed by the CCK8 assay; (D) Transwell assay analyzed the migration of H1299 cells co-cultured with CAF0 and CAF8; (E) The histogram showed the number of transmembrane H1299 cells in two groups. (T-test, data are presented as the mean ± S.D. *P < 0.05, **P < 0.01).