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. 2022 Oct 31;12(10):e059626. doi: 10.1136/bmjopen-2021-059626

Table 1.

Clinical characteristics of the infants hospitalised for acute bronchiolitis in a tertiary university paediatric hospital in Paris (France) between 2017 and 2021

Pre-COVID-19 period COVID-19 period P value*
2017–2018 2018–2019 2019–2020 2017–2020 aggregated data 2020–2021
Infants, n 479 451 417 1347 205
Age (months): median (IQR) 2.8 (1.5–4.9) 2.6 (1.4–4.8) 2.4 (1.3–4.4) 2.5 (1.4–4.7) 2.7 (1.5–4.7) 0.7
Gender: boys, n (%) 279 (58.2) 249 (55.2) 244 (58.5) 772 (57) 119 (58) 0.5
Comorbidities, n (%) 66 (14) 66 (15) 53 (13) 185 (14) 16 (8) 0.02
Weight (kg): median (IQR) 5.6 (4.4–6.9) 5.5 (4.6–7.0) 5.4 (4.3–7.0) 5.5 (4.4–7.0) 5.7 (4.5–6.9) 0.6
Evolution
Duration of hospitalisation (days), median (IQR) 2.4 (1.2–4.0) 3.0 (2.0–4.0) 3.9 (2.0–5.0) 3.0 (2.0–4.9) 3.0 (1.5–4.2) 0.3
 Oxygen therapy, n (%) 259 (54) 237 (52) 257 (61) 753 (56) 93 (45) 0.01
 Intensive care unit, n (%) 48 (13) 42 (9) 67 (16) 157 (12) 21 (11) 0.6
  Non-invasive ventilation, n (%) 42 (8) 38 (8) 67 (16) 147 (11) 22 (12) 0.9
  Invasive ventilation, n (%) 5 (1) 5 (1) 7 (1.6) 17 (1.2) 3 (1.7) 0.6
 Extracorporeal circulation, n (%) 2 (0.4) 0 (0) 2 (0.4) 4 (0.2) 0 (0) 0.4

*P value for the comparison between pre-COVID-19 aggregated data and COVID-19 data using χ2 test for categorical variables and Mann-Whitney test for continuous variables.