Table 1.
Clinical baseline characteristics of all participants.
Parameters | Control group (n = 18) | PCOS group (n = 32) |
---|---|---|
Age (Years) | 29.89 ± 3.36 | 29.34 ± 2.88 |
BMI | 20.44 ± 2.20 | 23.46 ± 3.67** |
T (μg/L) | 0.44 ± 0.15 | 0.68 ± 0.30* |
DHEAS (μg/dL) | 190.30 ± 45.85 | 270.15 ± 83.75** |
SHBG (nmol/L) | 88.75 ± 21.08 | 48.00 ± 20.20** |
FAI | 0.57 ± 0.35 | 2.10 ± 2.74** |
E2 (pmol/L) | 235.83 ± 261.42 | 233.66 ± 129.57 |
LH (IU/L) | 5.51 ± 1.92 | 10.75 ± 9.64* |
FSH (IU/L) | 7.28 ± 1.90 | 6.69 ± 1.66 |
LH/FSH | 0.76 ± 0.24 | 1.57 ± 1.15** |
AMH (μg/L) | 3.19 ± 0.79 | 8.12 ± 4.60*** |
PRL (μg/L) | 13.07 ± 4.59 | 13.02 ± 5.57 |
FBG (mmol/L) | 4.63 ± 0.66 | 5.30 ± 0.34** |
FSIns (mIU/L) | 4.53 ± 2.20 | 9.70 ± 5.54** |
HOMA-IR | 0.92 ± 0.42 | 2.29 ± 1.35** |
TCHO (mmol/L) | 4.82 ± 0.79 | 5.17 ± 0.91 |
TG (mmol/L) | 1.06 ± 0.86 | 1.11 ± 0.66 |
LDL (mmol/L) | 2.65 ± 0.41 | 3.00 ± 0.78 |
HDL (mmol/L) | 1.62 ± 0.34 | 1.48 ± 0.25 |
CRP (mg/L) | 1.36 ± 0.42 | 3.01 ± 2.47** |
BMI, body mass index; T, total testosterone; DHEAS, dehydroepiandrosterone sulfate; SHBG, sex hormone binding globulin; FAI, free androgen index (FAI = T × 100/SHBG); E2, estradiol; LH, luteinizing hormone; FSH, follicle-stimulating hormone; LH/FSH, the ratio of LH to FSH; AMH, Anti-Mullerian hormone; PRL, prolactin; FBG, fasting blood glucose; FSIns, fasting serum insulin; HOMA-IR, homeostasis model assessment of insulin resistance (HOMA-IR = FBG × FSIns/22.5); TCHO, total cholesterol; TG, triglyceride; LDL, low-density lipoprotein; HDL, high-density lipoprotein; CRP, and C-reactive protein. Data are presented as mean ± standard deviation. The difference between PCOS and healthy controls is compared by the independent-samples T test approach, and p < 0.05 is considered as statistical significance.
p < 0.05;
p < 0.01;
p < 0.001.