Table 3.

Unadjusted and Adjusted Clinical Outcomes According to an Additional SB-Opening Procedure

	Event Rates∗ at 5 Years		Unadjusted		IPTW Adjusted
	Simple Crossover (n = 1,685)	SB Opening (n = 509)	HR† (95% CI)	p Value	HR† (95% CI)	p Value
Primary outcome
Target lesion failure‡	95 (7.0)	29 (6.7)	0.99 (0.66–1.48)	0.947	0.68 (0.37–1.26)	0.218
Secondary outcomes
Death from any cause	77 (5.4)	17 (3.9)	0.75 (0.46–1.23)	0.252	0.77 (0.37–1.62)	0.494
Cardiac	43 (3.0)	12 (2.8)	0.93 (0.5–1.72)	0.822	0.98 (0.41–2.38)	0.970
Noncardiac	32 (2.3)	5 (1.1)	0.53 (0.23–1.26)	0.150	0.52 (0.13–2.04)	0.346
MI	22 (1.5)	11 (2.4)	1.36 (0.68–2.74)	0.386	1.45 (0.51–4.08)	0.482
Target vessel MI	12 (0.8)	6 (1.4)	1.38 (0.54–3.57)	0.501	1.36 (0.33–5.55)	0.670
Any revascularization	133 (9.7)	42 (9.7)	1.01 (0.72–1.42)	0.955	0.83 (0.49–1.42)	0.502
Target lesion	52 (4.0)	15 (3.5)	0.92 (0.52–1.63)	0.776	0.59 (0.24–1.43)	0.244
Target vessel	86 (6.4)	30 (7.0)	1.15 (0.76–1.72)	0.514	0.75 (0.4–1.38)	0.351
Definite stent thrombosis	16 (1.0)	3 (0.7)	0.76 (0.26–2.26)	0.626	0.98 (0.21–4.59)	0.985

Values are n (%) unless noted otherwise.

HR = hazard ratio; IPTW = inverse probability of treatment weighting; other abbreviation as in Figures 1 and 3.

^∗Event rates are based on Kaplan-Meier estimates.

^†HRs are for the SB-opening group compared with the simple crossover group.

^‡Target lesion failure was defined as a composite of death by cardiac causes, target vessel MI, or target lesion revascularization.