Central Illustration.

A Machine-Learning–Based Photoplethysmography Technology Facilitated Accurate Advance Real-Time Prediction of Atrial Fibrillation Onset

AF = atrial fibrillation; AUC = area under the receiver operating characteristic curve; ECG = electrocardiography; mAFA, mobile Health Technology for Improved Screening, Patient Involvement And Optimizing Integrated Care in Atrial Fibrillation; M1 = primary AF ML model; M2 = optimized AF ML model; ML = machine learning; NPV = negative predictive value; PPG = photoplethysmography; PPV = positive predictive value.