Central Illustration.

Brugada Syndrome

This illustration shows the flow from diagnosis to treatment of Brugada Syndrome (BrS). BrS is diagnosed with a spontaneously type 1 Brugada electrocardiogram (ECG) or type 1 Brugada ECG after provocative drug test. Ventricular fibrillation (VF) induction with up to double extra stimulation, family history of sudden cardiac death, SCN5A mutations, and ECG parameters are helpful for risk stratification. Recently, the scoring method, which combines several risks, is also used. In cases of secondary prevention, implantable cardioverter-defibrillator (ICD) is indicated, and in asymptomatic cases, oral administration of quinidine is performed depending on risk stratification in addition to lifestyle guidance.