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. 2021 Aug 28;1(2):129–146. doi: 10.1016/j.jacasi.2021.08.003

Central Illustration.

Central Illustration

Consensus Pathway on Novel Therapy for Type 2 Diabetes

SGLT2 inhibitors include those with proven efficacy, including empagliflozin, canagliflozin, and dapagliflozin. GLP-1RAs include those with proven efficacy, including liraglutide, semaglutide, and dulaglutide. ASCVD = atherosclerotic cardiovascular disease; eGFR = estimated glomerular filtration rate (mL/min/1.73 m2); GLP-1 RA = glucagon-like peptide 1 receptor agonist; HF = heart failure; LVEF = left ventricular ejection fraction; PCE = Pooled Cohort Equation; RF = risk factor; SGLT2 i = sodium-glucose cotransporter 2 inhibitor.