Table 5.
Association of Δ Hemoglobin (per-1 g/dL Increase) With Coronary Atherosclerotic Changes According to Baseline Hemoglobin
| Annualized Total PVC |
|||
|---|---|---|---|
| β (95% CI) | SE | P Value | |
| Overall | |||
| Model 1 | −2.173 (−3.459 to −0.887) | 0.655 | 0.001 |
| Model 2 | −1.999 (−3.270 to −0.728) | 0.647 | 0.002 |
| Model 3 | −1.642 (−2.924 to −0.360) | 0.653 | 0.012 |
| Model 4 | −1.707 (−2.975 to −0.439) | 0.646 | 0.008 |
| The composite of I and II | |||
| Model 1 | −2.045 (−3.669 to −0.421) | 0.826 | 0.014 |
| Model 2 | −2.251 (−3.903 to −0.599) | 0.841 | 0.008 |
| Model 3 | −2.226 (−3.852 to −0.600) | 0.827 | 0.007 |
| Model 4 | −2.401 (−4.053 to −0.749) | 0.840 | 0.004 |
| The composite of III and IV | |||
| Model 1 | −2.297 (−4.576 to −0.017) | 1.159 | 0.048 |
| Model 2 | −1.242 (−3.509 to 1.024) | 1.153 | 0.282 |
| Model 3 | −0.628 (−2.767 to 1.511) | 1.088 | 0.564 |
| Model 4 | −0.549 (−2.647 to 1.548) | 1.066 | 0.607 |
Model 1: Unadjusted. Model 2: Adjusted for age, sex, and traditional risk factors including hypertension, diabetes, hyperlipidemia, overweight or obesity, and current smoking. Model 3: Adjusted for age, sex, traditional risk factors including hypertension, diabetes, hyperlipidemia, overweight or obesity, current smoking, baseline hemoglobin levels, and baseline total plaque volume. Model 4: Adjusted for age, sex, traditional risk factors including hypertension, diabetes, hyperlipidemia, overweight or obesity, current smoking, baseline hemoglobin and creatinine levels, baseline total plaque volume, and the use of aspirin, beta-blocker, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, and statin.