Table 2.
All HCM Patients (n = 114) | Male HCM Patients (n = 83) | Female HCM Patients (n = 31) | P Value | |
---|---|---|---|---|
Clinical characteristics | ||||
Age, y | 52 ± 13 | 52 ± 14 | 53 ± 12 | 0.570 |
Race | 0.749 | |||
Chinese | 100 (88) | 72 (87) | 28 (90) | |
Malay | 6 (5) | 4 (5) | 2 (6) | |
Indian | 8 (7) | 7 (8) | 1 (3) | |
Height, m | 1.68 ± 0.08 | 1.71 ± 0.06 | 1.59 ± 0.06 | <0.001 |
Weight, kg | 71 ± 14 | 75 ± 12 | 60 ± 13 | <0.001 |
Body surface area, m2 | 1.80 ± 0.19 | 1.87 ± 0.15 | 1.61 ± 0.17 | <0.001 |
Systolic blood pressure, mm Hg | 134 ± 20 | 136 ± 18 | 128 ± 24 | 0.044 |
Diastolic blood pressure, mm Hg | 77 ± 12 | 79 ± 12 | 73 ± 11 | 0.018 |
CMR characteristics | ||||
Indexed LV EDV, mL/m2 | 79 ± 12 | 80 ± 13 | 78 ± 10 | 0.312 |
Indexed LV ESV, mL/m2 | 33 ± 9 | 34 ± 10 | 32 ± 9 | 0.419 |
Indexed LV SV, mL/m2 | 46 ± 9 | 46 ± 9 | 45 ± 8 | 0.587 |
Indexed LV mass, g/m2 | 81 ± 26 | 85 ± 26 | 70 ± 21 | 0.006 |
LV ejection fraction, % | 58 ± 9 | 58 ± 9 | 59 ± 9 | 0.701 |
Indexed RV EDV, mL/m2 | 72 ± 16 | 74 ± 16 | 66 ± 15 | 0.016 |
Indexed RV ESV, mL/m2 | 27 ± 12 | 29 ± 12 | 23 ± 10 | 0.010 |
Indexed RV SV, mL/m2 | 45 ± 9 | 45 ± 9 | 43 ± 8 | 0.310 |
RV ejection fraction, % | 63 ± 10 | 62 ± 10 | 67 ± 10 | 0.025 |
Global longitudinal strain, % | −11.8 ± 3.1 | −11.6 ± 3.3 | −12.2 ± 2.5 | 0.386 |
Global radial strain, % | 29.1 ± 9.4 | 27.9 ± 8.9 | 32.4 ± 9.7 | 0.025 |
Global circumferential strain, % | −16.9 ± 3.6 | −16.5 ± 3.7 | −18.0 ± 3.4 | 0.062 |
LV mass/EDV | 1.03 ± 0.29 | 1.07 ± 0.30 | 0.91 ± 0.25 | 0.009 |
WTMax, mm | 15.0 ± 3.3 | 15.2 ± 3.4 | 14.7 ± 3.0 | 0.484 |
Indexed WTMax, mm/m2 | 8.5 ± 2.0 | 8.2 ± 2.0 | 9.2 ± 1.8 | 0.018 |
Asymmetric ratio | 1.97 ± 0.80 | 1.78 ± 0.61 | 2.47 ± 1.02 | <0.001 |
Nonischemic fibrosis | 87 (76) | 61 (73) | 26 (84) | 0.600 |
Native T1, ms | 1,058 ± 41 | 1,050 ± 40 | 1,080 ± 37 | 0.007 |
Extracellular volume fraction, % | 30.4 ± 4.4 | 29.5 ± 4.0 | 32.9 ± 4.7 | 0.005 |
Values are mean ± SD or n (%).
HCM = hypertrophic cardiomyopathy; other abbreviations as in Table 1.