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. 2021 Sep 21;1(2):218–226. doi: 10.1016/j.jacasi.2021.07.001

Table 2.

Clinical and Baseline Characteristics of Patients with HCM

All HCM Patients (n = 114) Male HCM Patients (n = 83) Female HCM Patients (n = 31) P Value
Clinical characteristics
 Age, y 52 ± 13 52 ± 14 53 ± 12 0.570
 Race 0.749
 Chinese 100 (88) 72 (87) 28 (90)
 Malay 6 (5) 4 (5) 2 (6)
 Indian 8 (7) 7 (8) 1 (3)
 Height, m 1.68 ± 0.08 1.71 ± 0.06 1.59 ± 0.06 <0.001
 Weight, kg 71 ± 14 75 ± 12 60 ± 13 <0.001
 Body surface area, m2 1.80 ± 0.19 1.87 ± 0.15 1.61 ± 0.17 <0.001
 Systolic blood pressure, mm Hg 134 ± 20 136 ± 18 128 ± 24 0.044
 Diastolic blood pressure, mm Hg 77 ± 12 79 ± 12 73 ± 11 0.018
CMR characteristics
 Indexed LV EDV, mL/m2 79 ± 12 80 ± 13 78 ± 10 0.312
 Indexed LV ESV, mL/m2 33 ± 9 34 ± 10 32 ± 9 0.419
 Indexed LV SV, mL/m2 46 ± 9 46 ± 9 45 ± 8 0.587
 Indexed LV mass, g/m2 81 ± 26 85 ± 26 70 ± 21 0.006
 LV ejection fraction, % 58 ± 9 58 ± 9 59 ± 9 0.701
 Indexed RV EDV, mL/m2 72 ± 16 74 ± 16 66 ± 15 0.016
 Indexed RV ESV, mL/m2 27 ± 12 29 ± 12 23 ± 10 0.010
 Indexed RV SV, mL/m2 45 ± 9 45 ± 9 43 ± 8 0.310
 RV ejection fraction, % 63 ± 10 62 ± 10 67 ± 10 0.025
 Global longitudinal strain, % −11.8 ± 3.1 −11.6 ± 3.3 −12.2 ± 2.5 0.386
 Global radial strain, % 29.1 ± 9.4 27.9 ± 8.9 32.4 ± 9.7 0.025
 Global circumferential strain, % −16.9 ± 3.6 −16.5 ± 3.7 −18.0 ± 3.4 0.062
 LV mass/EDV 1.03 ± 0.29 1.07 ± 0.30 0.91 ± 0.25 0.009
 WTMax, mm 15.0 ± 3.3 15.2 ± 3.4 14.7 ± 3.0 0.484
 Indexed WTMax, mm/m2 8.5 ± 2.0 8.2 ± 2.0 9.2 ± 1.8 0.018
 Asymmetric ratio 1.97 ± 0.80 1.78 ± 0.61 2.47 ± 1.02 <0.001
 Nonischemic fibrosis 87 (76) 61 (73) 26 (84) 0.600
 Native T1, ms 1,058 ± 41 1,050 ± 40 1,080 ± 37 0.007
 Extracellular volume fraction, % 30.4 ± 4.4 29.5 ± 4.0 32.9 ± 4.7 0.005

Values are mean ± SD or n (%).

HCM = hypertrophic cardiomyopathy; other abbreviations as in Table 1.