Table 2.
Association between baseline abdominal obesity indices and incident cardiovascular events in people with type 2 diabetes
| Indices | Event/ Total |
Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | ||
| WC | |||||||
| Per 1 SD increase | 289/2328 | 1.52 (1.37–1.69) | < 0.001 | 1.59 (1.41–1.80) | < 0.001 | 1.57(1.39–1.78) | < 0.001 |
| Quartiles | |||||||
| Q1(≤ 84.10) | 33/614 | 1.00 | 1.00 | 1.00 | |||
| Q2(84.20–90.00) | 59/599 | 1.89 (1.23–2.89) | 0.003 | 1.75 (1.14–2.68) | 0.010 | 1.72 (1.12–2.65) | 0.013 |
| Q3(90.10–98.00) | 85/559 | 2.99 (2.00–4.47) | < 0.001 | 2.95 (1.97–4.43) | < 0.001 | 2.88 (1.92–4.32) | < 0.001 |
| Q4(> 98.00) | 112/556 | 4.05 (2.75–5.97) | < 0.001 | 4.10 (2.74–6.12) | < 0.001 | 3.92 (2.62–5.88) | < 0.001 |
| VAI | |||||||
| Per 1 SD increase | 289/2328 | 1.09 (1.05–1.13) | < 0.001 | 1.11 (1.07–1.16) | < 0.001 | 1.11 (1.06–1.16) | < 0.001 |
| Quartiles | |||||||
| Q1(≤ 1.14) | 22/582 | 1.00 | 1.00 | 1.00 | |||
| Q2(1.15–1.76) | 66/582 | 3.11 (1.92–5.04) | < 0.001 | 3.09 (1.90–5.02) | < 0.001 | 3.03 (1.86–4.93) | < 0.001 |
| Q3(1.77–2.66) | 79/582 | 3.77 (2.35–6.04) | < 0.001 | 4.10 (2.54–6.64) | < 0.001 | 3.97 (2.45–6.44) | < 0.001 |
| Q4(> 2.66) | 122/582 | 6.11 (3.88–9.62) | < 0.001 | 7.14 (4.46–11.41) | < 0.001 | 6.88 (4.27–11.07) | < 0.001 |
| LAP | |||||||
| Per 1 SD increase | 289/2328 | 1.41 (1.32–1.50) | < 0.001 | 1.47 (1.37–1.57) | < 0.001 | 1.46 (1.36–1.57) | < 0.001 |
| Quartiles | |||||||
| Q1(≤ 26.00) | 24/583 | 1.00 | 1.00 | 1.00 | |||
| Q2(26.01–41.15) | 56/581 | 2.40 (1.49–3.88) | < 0.001 | 2.51 (1.55–4.06) | < 0.001 | 2.50 (1.54–4.04) | < 0.001 |
| Q3(41.16–65.00) | 82/582 | 3.58 (2.27–5.64) | < 0.001 | 3.71 (2.35–5.88) | < 0.001 | 3.65 (2.30–5.80) | < 0.001 |
| Q4(> 65.00) | 127/582 | 5.84 (3.78–9.04) | < 0.001 | 6.18 (3.96–9.63) | < 0.001 | 6.03 (3.85–9.47) | < 0.001 |
| CVAI | |||||||
| Per 1 SD increase | 289/2328 | 1.87 (1.68–2.08) | < 0.001 | 1.80 (1.60–2.04) | < 0.001 | 1.78 (1.57–2.01) | < 0.001 |
| Quartiles | |||||||
| Q1(≤ 96.58) | 19/582 | 1.00 | 1.00 | 1.00 | |||
| Q2(96.59–121.59) | 43/582 | 2.34 (1.37–4.02) | 0.002 | 1.88 (1.09–3.24) | 0.023 | 1.91 (1.11–3.30) | 0.020 |
| Q3(121.60–146.38) | 89/582 | 5.05 (3.08–8.29) | < 0.001 | 3.81 (2.31–6.28) | < 0.001 | 3.71 (2.24–6.15) | < 0.001 |
| Q4(> 146.38) | 138/582 | 8.14 (5.04–13.15) | < 0.001 | 5.86 (3.61–9.53) | < 0.001 | 5.67 (3.47–9.27) | < 0.001 |
Model 1: crude model; Model 2: adjusted for gender, age, ethnicity, education, smoking status, and drinking status; Model 3: adjusted for gender, age, ethnicity, education, smoking status, drinking status, low-density lipoprotein cholesterol, total cholesterol, fasting blood glucose, systolic blood pressure, diastolic blood pressure, physical activity, antidiabetic agents, and diabetes duration
HR hazard ratio, CI confidence interval, SD standard deviation, WC waist circumference, VAI visceral adiposity index, LAP lipid accumulation product, CVAI Chinese visceral adiposity index