Table 3.

Univariable logistic regression analysis between clinical-pathological characteristics and BRCA1/2 mutations

Characteristics	OR	95% CI	P
Age (year)
> 45	Reference
≤ 45	6.088	2.042–18.149	0.0012
Menophania (year)
> 13	Reference
≤ 13	1.750	0.627–4.884	0.2853
Menopausal status
Postmenopausal	Reference
Pre-menopausal	0.500	0.154–1.619	0.2476
Lactation time (month)
> 10	Reference
≤ 10	1.922	0.669–5.521	0.225
Family history
negative	Reference
positive	1.896	0.543–6.618	0.3159
Interval time (year)
< 2	Reference
≥ 2	3.922	1.228–12.532	0.0211
First tumor size
≤T2	Reference
≥T2	0.886	0.321–2.449	0.8160
First tumor nodal status
positive	Reference
negative	1.827	0.651–5.126	0.2521
Second tumor size
≤T2	Reference
≥T2	0.855	0.297–2.465	0.772
Second tumor nodal status
positive	Reference
negative	0.750	0.280–2.008	0.567
Same histologic type in both tumors
no	Reference
yes	0.614	0.214–1.762	0.3643
Same HR status in both tumor
no	Reference
yes	1.476	0.484–4.505	0.4939
Same HER2 status in both tumor
no	Reference
yes	> 999.999	< 0.001->999.999	0.9534
At least one HR (-) tumor
no	Reference
yes	1.590	0.607–4.168	0.3457
At least one HER2 (-) tumor
no	Reference
yes	4.171	0.524–33.204	0.1773
At least one TNBC
no	Reference
yes	4.296	1.533–12.038	0.0056
At least one medullary carcinoma
no	Reference
yes	18.000	1.768-183.287	0.0146
Both HR (-) tumor
no	Reference
yes	5.389	1.461–19.883	0.0114
Both HER2 (-) tumor
no	Reference
yes	4.949	1.746–14.030	0.0026
Both TNBC
no	Reference
yes	> 999.999	< 0.001->999.999	0.9707