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. 2022 Jul 18;55(11):e13315. doi: 10.1111/cpr.13315

FIGURE 1.

FIGURE 1

FGF10 is upregulated in UVB‐induced skin injury. (A) The method of UVB radiation treatment in C57BL/6J mice experimental model. (B) Skin injury induced by UVB radiation. Skin of wild‐type (WT) C57BL/6J mice (Left). Skin of UVB radiation C57BL/6J mice (Right). (C) HE staining of wild‐type (WT) C57BL/6J mice and UVB radiation C57BL/6J mice. (n = 5). Scale bars = 100 μm. (D) Immunohistochemical staining of wild‐type (WT) C57BL/6J mice and UVB radiation C57BL/6J mice. The positive staining (brown) demonstrated positive expression (n = 5). Scale bars = 100 μm. (E) Quantification of epidermal thickness from (C). (F) Quantification of AOD from (D). (G) Quantified by quantitative real‐time PCR (qRT‐PCR) in untreated skin and UVB treated skin. The skin of epidermis and dermis were counted separately (n = 5). The data are presented as the means ± SEM. ### P < 0.001, ***P < 0.001, **P < 0.01, *P < 0.05, vs. the corresponding UVB untreated group; N.S., nonsignificant