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. 2022 Jul 18;55(11):e13315. doi: 10.1111/cpr.13315

FIGURE 2.

FIGURE 2

FGF10 overexpression alleviates UVB‐induced skin injury. (A) HE staining of AAV‐GFP or AAV‐Fgf10 treated with or without UVB (n = 3). Scale bars = 100 μm. (B) Immunohistochemical staining of PCNA in the skin of AAV‐GFP or AAV‐Fgf10 treated with or without UVB. The positive staining (brown) demonstrated positive expression (n = 3). Scale bars = 100 μm. (C) Representative IHC of Col1a1 in the skin of AAV‐GFP or AAV‐Fgf10 treated with or without UVB. The positive staining (brown) demonstrated positive expression (n = 3). Scale bars = 20 μm. (D) Immunofluorescence staining of γ‐H2AX in the skin of AAV‐GFP or AAV‐Fgf10 treated with or without UVB (n = 3). Scale bars = 100 μm. (E) Quantification of epidermal thickness from (A). (F) Quantification of AOD from (B). (G) Quantification of AOD from (C). (H) Quantification percentage of γ‐H2AX‐positive from (D). The data were presented as the means ± SEM. ***P < 0.001, **P < 0.01, ### P < 0.001, ## P < 0.01, # P < 0.05, vs. the corresponding UVB untreated AAV‐GFP group