Table 2.

Pooled incidence rates of grade ≥ 3 cytopaenias

Grade ≥ 3 cytopaenia	LD regimen	Rate	95% CI
Anaemia	High dose	0.81	(0.71–0.90)
	Low dose	0.58	(0.28–0.87)
	Overall	0.65	(0.48–0.83)
Febrile neutropaenia	High dose	0.64	(0.50–0.78)
	Low dose	0.39	(0.25–0.53)
	Overall	0.54	(0.40–0.68)
Neutropaenia	High dose	0.88	(0.76–1.0)
	Low dose	0.78	(0.67–0.89)
	Overall	0.82	(0.74–0.90)
Thrombocytopaenia	High dose	0.66	(0.35–0.97)
	Low dose	0.64	(0.48–0.81)
	Overall	0.64	(0.49–0.79)
Lymphopaenia	High dose	1.00	NR
	Low dose	0.57	(0.42–0.73)
	Overall	0.6	(0.47–0.73)