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. 2022 Nov 2;57(Suppl 1):100–416. doi: 10.1038/s41409-022-01798-0
Parameters (n = 43) Number (%) or median (min-max)
Age (year) 56 (25-73)
Gender (Female/Male) 14/29
Disease Multiple Myeloma 26 (60,4)
Hodgkin Lymphoma 4 (9,4)
Non-Hodgkin Lymphoma 13 (30,2)
Pre-transplant chemotherapy line ≤3 37 (86)
>3 6 (14)
Pre-transplant response to therapy Complete remission 35 (81,3)
Partial remission 7 (16,2)
Stabil disease 1 (2,5)
CMV status pre-transplant CMV IgG positive 43 (100)
CMV IgM positive 0 (0)
Engraftment time (day) Neutrophil count 12 (9-51)
>500/mm3 14 (8-51)
CMV reactivation in the study cohort Platelet count > 20000/mm3 43 (11,9)
Yes 317 (88,1)
No
Reason for checking CMV level Prolonged fever 14 (32,5)
Diarrhea 5 (11,6)
Pneumonia 9 (20,9)
Liver enzyme elevation 6 (14,1)
Cytopenia 9 (20,9)
Time to reactivation (day) 39 (8-1825)
CMV antigenemia (IU/mL) Moment of diagnosis 467 (27-36385)
Peak level 482 (27-78987)
Anti-CMV therapy Ganciclovir 12 (57,1)
Valganciclovir 9 (42,9)
Treatment-related toxicity Neutropenia 2 (20)
Pancytopenia 2 (20)
Hypomagnesemia 3 (30)
Hypocalcemia 2 (20)
Acute kidney failure 1 (10)
Anti-CMV therapy (day) Induction therapy 14 (7-28)
Maintenance therapy 14 (7-32)
Development of CMV disease Yes 6 (13,9)
No 37 (86,1)
Mortality (%) 100-day 6,9
Overall 46,5