CLL patients with SHG	CLL patients without SHG
	(n = 18)	(n = 90)	p
Infection numbers	12	25	0.003
IgG at diagnosis	909 ± 464	1125 ± 359	0.031
IgG before treatment	750 (330- 1360)	1000 (355 – 2390)	0.001
IgG at last status	452.5(120-1220)	896 (285 – 1892)	<0.001
Receiving treatment	17, 94.4%	56, 62%	0.006
Chlorambucil-prednisolone	8,44.4%	16,17.7%	0.003
FCR	6, 33.3%	9, 10%	0.02
Venetoclax	3,16.6%	1,1.1%	0.014
Ibrutinib	13,72.2%	24,26.6%	0.001