Period |
August 2009-December 2021 |
n: 21 |
Total tx: 513 |
|
Autologous tx: 373 (MM + Lymphoma) |
|
MM: 274 |
|
Lymphoma: 99 |
|
Mob regimen(G-CSF/Chemotherapy+G-CSF): 252 |
|
Required third step mob. regimen: 21/373 (7.6%) |
Age, median (min-max) |
51 (21-66) |
Female/Male |
6/15 (29%/ 71 %) |
Diagnosis |
MM: |
6 (29%) |
Lymphoma:(NHL + HD): (12 + 3) |
15 (71%) |
Day 1,CD34 + cells count (post-plerixafor) |
32 (5.8-92) |
Median days of apheresis (day) |
2 (2-3) |
1 |
0 |
2 |
12 (75 %) |
3 |
1 |
Total Yield CD34 + x 106 cells/kg |
(min-max) |
4.72 (1.3-7.17) |
Not processed: |
4 (19%) |
<2 : |
2 (9.5 %) |
>2-4: |
4 (19 %) |
>4-6: |
11 (52.3%) |
Successful mobilization |
16 (76 %) |
Mobilization failure |
5 (24 %) |
Patients undergoing transplantation |
16 (76 %) |
Median time to engraftment (day), (min-max) |
Neutrophil> 500: 12 (9-17) |
11/16 (69 %) |
Platelet > 20 000: 17 (12-30) |
8/16 (50 %) |
Platelet > 50 000: 35 (17-95) |
7/16 (44 %) |
Adverse events |
Diarrhea |
1 (4.7 %) |
Nause |
1 (4.7 %) |