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. 2022 Nov 2;57(Suppl 1):100–416. doi: 10.1038/s41409-022-01798-0
Variable All Patients Flu/Mel/Thio Flu/Mel/TBI P-Value
(N = 134) (N = 64) (N = 70)
Age at transplant
 <55 years 71 (52.99%) 33 (51.56%) 38 (54.29%) 0.863
 ≥55 years 63 (47.01%) 31 (48.44%) 32 (45.71%)
Gender
 Male 82 (61.19%) 40 (62.50%) 42 (60.00%) 0.86
 Female 52 (38.81%) 24 (37.50%) 28 (40.00%)
Disease Subtype
 AML/MDS 103 (76.87%) 48 (75.00%) 55 (78.57%) 0.684
 ALL 31 (23.13%) 16 (25.00%) 15 (21.43%)
KPS at transplant
 KPS 90 - 100 65 (57.52%) 38 (71.70%) 27 (45.00%) 0.005
 KPS < 90 48 (42.48%) 15 (28.30%) 33 (55.00%)
DRI
 Low/Intermediate DRI 76 (57.14%) 32 (50.00%) 44 (63.77%) 0.118
 High/Very High DRI 57 (42.86%) 32 (50.00%) 25 (36.23%)
HCT-CI
 HCT-CI ≤ 3 83 (61.94%) 39 (60.94%) 44 (62.86%) 0.86
 HCT-CI > 3 51 (38.06%) 25 (39.06%) 26 (37.14%)
Melphalan dose
 100 mg/m2 68 (50.75%) 25 (39.06%) 43 (61.43%) 0.015
 140 mg/m2 66 (49.25%) 39 (60.94%) 27 (38.57%)
Patient CMV status
 Seropositive 122 (91.04%) 59 (92.19%) 63 (90.00%) 0.767
 Seronegative 12 (8.96%) 5 (7.81%) 7 (10.00)
Stem cell source
 Bone marrow 117 (87.31%) 60 (93.75%) 57 (81.43%) 0.039
 Peripheral blood 17 (12.69%) 4 (6.25%) 13 (18.57%)