Variable | All Patients | Flu/Mel/Thio | Flu/Mel/TBI | P-Value |
---|---|---|---|---|
(N = 134) | (N = 64) | (N = 70) | ||
Age at transplant | ||||
<55 years | 71 (52.99%) | 33 (51.56%) | 38 (54.29%) | 0.863 |
≥55 years | 63 (47.01%) | 31 (48.44%) | 32 (45.71%) | |
Gender | ||||
Male | 82 (61.19%) | 40 (62.50%) | 42 (60.00%) | 0.86 |
Female | 52 (38.81%) | 24 (37.50%) | 28 (40.00%) | |
Disease Subtype | ||||
AML/MDS | 103 (76.87%) | 48 (75.00%) | 55 (78.57%) | 0.684 |
ALL | 31 (23.13%) | 16 (25.00%) | 15 (21.43%) | |
KPS at transplant | ||||
KPS 90 - 100 | 65 (57.52%) | 38 (71.70%) | 27 (45.00%) | 0.005 |
KPS < 90 | 48 (42.48%) | 15 (28.30%) | 33 (55.00%) | |
DRI | ||||
Low/Intermediate DRI | 76 (57.14%) | 32 (50.00%) | 44 (63.77%) | 0.118 |
High/Very High DRI | 57 (42.86%) | 32 (50.00%) | 25 (36.23%) | |
HCT-CI | ||||
HCT-CI ≤ 3 | 83 (61.94%) | 39 (60.94%) | 44 (62.86%) | 0.86 |
HCT-CI > 3 | 51 (38.06%) | 25 (39.06%) | 26 (37.14%) | |
Melphalan dose | ||||
100 mg/m2 | 68 (50.75%) | 25 (39.06%) | 43 (61.43%) | 0.015 |
140 mg/m2 | 66 (49.25%) | 39 (60.94%) | 27 (38.57%) | |
Patient CMV status | ||||
Seropositive | 122 (91.04%) | 59 (92.19%) | 63 (90.00%) | 0.767 |
Seronegative | 12 (8.96%) | 5 (7.81%) | 7 (10.00) | |
Stem cell source | ||||
Bone marrow | 117 (87.31%) | 60 (93.75%) | 57 (81.43%) | 0.039 |
Peripheral blood | 17 (12.69%) | 4 (6.25%) | 13 (18.57%) |