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. 2022 Nov 2;57(Suppl 1):100–416. doi: 10.1038/s41409-022-01798-0
All patients BuFlu TreoFlu p value
n = 97 n = 67 n = 30
Age, median (min-max) 57 (19-73) 54 (19-70) 62 (26-73) 0,003
Sex, n (%) 0,107
 Male 54 (55,7) 34 (50,7) 20 (66,7)
 Female 43 (44,3) 33 (49,3) 10 (33,3)
Diagnoses, n (%) 0,595
 AML 71 (73,2) 49 (73,1) 22 (73,3)
 MDS 26 (26,8) 18 (26,9) 8 (26,7)
Disease status, n (%) 0,260
 Complete remission 76 (78,4) 56 (83,6) 20 (66,7)
 Partial remission 5 (5,2) 3 (4,5) 2 (6,7)
 Progression/refractory 11 (11,3) 5 (7,5) 6 (20)
 Never treated 5 (5,2) 3 (4,5) 2 (6,7)
Prior treatment lines, median (min-max) 1 (0-4) 1 (0-4) 1 (0-3) 0,102
HCT-CI score, n (%) 0,037
<3 47 (48,5) 37 (55,2) 10 (33,3)
≥3 50 (51,5) 30 (44,8) 20 (66,7)
Donor, n (%) 0,566
HLA-matched sibling 29 (29,9) 22 (32,8) 7 (23,3)
HLA-haploidentical sibling 19 (19,6) 11 (16,4) 8 (26,7)
HLA-matched unrelated 44 (45,4) 30 (44,8) 14 (46,7)
HLA-mismatched unrelated 5 (5,2) 4 (6) 1 (3,3)
Stem cell source, n (%) 0,064
Bone marrow 64 (66) 48 (71,6) 16 (53,3)
Peripheral blood 33 (34) 19 (28,4) 14 (46,7)
GvHD prophilaxis, n (%) 0,243
Calcineurin inhibitor + MMF/MTX 67 (69,1) 46 (68,7) 21 (70)
Cy post + FK + MMF 20 (20,6) 12 (17,9) 8 (26,7)
Cy post 10 (10,3) 9 (13,4) 1 (3,3)
ATG 28 (28,9) 18 (26,9) 10 (33,3) 0,338