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. 2022 Nov 2;57(Suppl 1):100–416. doi: 10.1038/s41409-022-01798-0
Patient characteristics TBI-based regimen (n = 28) Non-TBI based regimen n = 32 p
Median age (range), years 28 (17-49) 32 (17-48) 0.31
Sex-ratio 1.33 3.6 0.08
Diagnosis 0.4
B-ALL, n (%) 14 (50%) 20 (62.5%)
T-ALL, n (%) 12 (43%) 10 (31.3%)
Mixed lineage leukemia, n (%) 2 (7%) 2 (6.2%)
Median time diagnosis-allo-HSCT (range), months 6 (2-137) 7 (3-41) 0.05
Disease status before transplant, n (%) 0.55
CR1 21 (75%) 26 (81%)
>CR1 7 (25%) 6 (19%)
HCT-CI score ≥ 2, n (%) 8 (28.6%) 3 (9.4%) 0.05
ABO mismatch, n (%) 0.55
Matched 18 (64.3%) 17 (53.2%)
Major or bidirectional or minor 10 (35.7%) 15 (46.8%)
Stem cell source, n (%) 0.35
Bone marrow 12(43%) 10(31%)
Peripheral blood stem cell 26(57%) 22(69%)
GVHD prophylaxis 0.92
Cyclosporine and methotrexate +/−ATG 27(96.4%) 31(96.9%)
Cyclosporine 1 (3.6%) 1 (3.1%)