Table 2.
Differences Between LC and Cirrhotic HCC
| Parameter | LC (n = 131) | Cirrhotic HCC (n = 96) | P value |
|---|---|---|---|
| Age (y) | 59(51–71) | 61(56–67) | 0.445 |
| Male (n) | 71 | 79 | <0.001 |
| Female (n) | 60 | 17 | |
| TBIL (μmol/L) | 26.8(18.9–47.7) | 22.6(16.3–44.3) | 0.204 |
| TP (g/L) | 57.2(51.6–62.9) | 59.8(54.9–65.0) | 0.02 |
| ALB (g/L) | 28.3(24.9–31.6) | 32.0(28.2–35.6) | <0.001 |
| ALP (U/L) | 95(68–152) | 114(82–172) | 0.03 |
| ALT (U/L) | 23.6(13.9, 41) | 31.4(21.6–55.6) | 0.001 |
| GGT (U/L) | 38(22–93) | 82(46–158) | <0.001 |
| AST (U/L) | 39(22, 60) | 46(31–90) | 0.002 |
| WBC (109/L) | 3.57(2.57, 5.87) | 5.14(3.83–6.65) | <0.001 |
| RBC 1012/L | 2.95(2.57–3.42) | 3.88(3.11–4.52) | <0.001 |
| HGB (g/L) | 90(73–104) | 116(99–135) | <0.001 |
| NLR | 2.80(1.71–4.87) | 3.44(1.98–6.21) | 0.083 |
| PLR | 81.00(57.53–122.39) | 99.61(65.22–150.56) | 0.064 |
| ALBI score = 1 | 3 | 8 | 0.026 |
| ALBI score = 2 | 74 | 61 | |
| ALBI score = 3 | 54 | 27 |
Abbreviations: LC, liver cirrhosis; HCC, hepatocellular carcinoma; TBIL, total bilirubin; TP, total protein; ALB, albumin; ALP, alkaline phosphatase; ALT, alanine transaminase; GGT, glutamyl transferase; AST, aspartate transaminase; WBC, white blood cell; RBC, red blood cell; HGB, hemoglobin; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; ALBI score, albumin-bilirubin score.