Table 3.
Differences Between Cirrhotic HCC and Non-Cirrhotic HCC
| Parameter | Total (n=136) | Cirrhotic HCC (n = 96) | Non-Cirrhotic HCC (n = 40) | P value |
|---|---|---|---|---|
| Age (y) | 63(56–71) | 61(56–67) | 70(59–77) | 0.002 |
| Male (n) | 108 | 79 | 29 | 0.198 |
| Female (n) | 28 | 17 | 11 | |
| TBIL (μmol/L) | 22.3(15.6–38.7) | 22.6(16.3–44.3) | 18.6(13.3–25.8) | 0.031 |
| TP (g/L) | 61.4(55.4–65.8) | 59.8(54.9–65.0) | 62.8(56.9–67.3) | 0.165 |
| ALB (g/L) | 32.4(28.4–36.7) | 32.0(28.2–35.6) | 34.8(30.0–38.4) | 0.023 |
| ALP (U/L) | 114(81–172) | 114(82–172) | 111(81–175) | 0.681 |
| ALT (U/L) | 31.4(21.5–62.6) | 31.4(21.6–55.6) | 31.1(19.3–82.8) | 0.767 |
| GGT (U/L) | 82(46–172) | 82(46–158) | 79(46–244) | 0.845 |
| AST (U/L) | 46(30–94) | 46(31–90) | 47(26–94) | 0.483 |
| WBC (109/L) | 5.35(3.92–7.13) | 5.14(3.83–6.65) | 6.45(4.74–7.73) | 0.053 |
| RBC 1012/L | 3.97(3.17–4.49) | 3.88(3.11–4.52) | 4.11(3.56–4.44) | 0.385 |
| HGB (g/L) | 119(101–134) | 116(99–135) | 125(110–131) | 0.428 |
| NLR | 3.52(2.03–6.01) | 3.44(1.98–6.21) | 3.52(2.18–5.41) | 0.729 |
| PLR | 109.68(73.42–174.24) | 99.61(65.22–150.56) | 143.39(108.38–192.99) | 0.002 |
| ALBI score = 1 | 15 | 8 | 7 | 0.072 |
| ALBI score = 2 | 89 | 61 | 28 | |
| ALBI score = 3 | 32 | 27 | 5 |
Abbreviations: HCC, hepatocellular carcinoma; TBIL, total bilirubin; TP, total protein; ALB, albumin; ALP, alkaline phosphatase; ALT, alanine transaminase; GGT, glutamyl transferase; AST, aspartate transaminase; WBC, white blood cell; RBC, red blood cell; HGB, hemoglobin; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; ALBI score, albumin-bilirubin score.