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. Author manuscript; available in PMC: 2022 Nov 2.
Published in final edited form as: Clin Infect Dis. 2021 Jul 15;73(2):e371–e379. doi: 10.1093/cid/ciaa875

Table 1.

Average annual incidence, average annual percent change in incidence, and case-fatality ratios for invasive H. influenzae serotype a disease, by age group—United States and Alaska, 2008–2017

Age (years) United States
Alaska
Estimated incidence (95% CI) Average annual percent change in incidence (95% CI) CFR, % Incidence (95% CI) Average annual percent change in incidence (95% CI) CFR, %
<1 1.60 (1.46-1.75) 14.6 (11.4-17.8) 6.2 24.73 (16.30-36.00) 1.2 (−11.2-15.3) 7.4
1-4 0.41 (0.36-0.45) 5.6 (2.8-8.5) 1.1 4.14 (2.45-6.54) 17.7 (−0.8-39.5) 11.1
5-17 0.03 (0.03-0.03) 7.8 (2.0-14.0) 5.0 0.07 (0.00-0.41) −1.0 (−29.8-39.5)a 0.0
18-34 0.02 (0.01-0.02) 16.4 (8.3-25.1) 14.3 0.00 (0.00-0.00) 0.0
35-49 0.05 (0.04-0.05) 4.0 (−0.1-8.3) 11.1 0.07 (0.00-0.41) 0.0
50-64 0.10 (0.10-0.11) 23.4 (19.5-27.3) 7.9 0.07 (0.00-0.41) 0.0
≥65 0.14 (0.14-0.15) 7.9 (5.0-10.9) 15.1 0.15 (0.00-0.85) 100.0
Total 0.10 (0.10-0.10) 11.1 (9.7-12.6) 7.8 0.68 (0.50-0.89) 4.9 (−5.0-15.8) 10.2

Abbreviations: CFR, case-fatality ratio; CI, confidence interval.

Note: Incidence presented in cases per 100,000 persons per year.

a

Due to small numbers, age groups were combined. This average annual percent change in incidence is for persons aged ≥5 years in Alaska.