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. 2022 May 11;32(7):938–948. doi: 10.4014/jmb.2112.12044

Fig. 1. CircCOL1A2 with a circular structure is upregulated in GC tissues.

Fig. 1

(A) GeoChip was utilized to screen out differentially expressed circRNAs in GC. (B) The expression of circCOL1A2 was detected by qPCR in HGC-27, AGS, MKN-45 and GSE-1 cells. (C) PCR-agarose gel electrophoresis detected the circular structure of circCOL1A2 in AGS and MKN-45 cells. (D) CircCOL1A2 and COL1A2 mRNA were detected by qPCR in RNase R-treated AGS and MKN-45 cells to assess the stability. One-way ANOVA and two-way ANOVA were used for comparison detection. **p < 0.01.