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. 2016 Jul 28;236:215–220. doi: 10.1016/j.jviromet.2016.07.024

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© 2016 Elsevier B.V. All rights reserved.

Elsevier has created a Monkeypox Information Center (https://www.elsevier.com/connect/monkeypox-information-center) in response to the declared public health emergency of international concern, with free information in English on the monkeypox virus. The Monkeypox Information Center is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its monkeypox related research that is available on the Monkeypox Information Center - including this research content - immediately available in publicly funded repositories, with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the Monkeypox Information Center remains active.

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Fig. 1 — Sequence alignments of target regions for the VARV ORF B12R (A), MPXV ORF F3L (B) and VZV ORF38 (C). The alignments of 169 (A), 49 (B) and 178 (C) strains were made using BioEdit Sequence Alignment Editor. Strains within one species with identical target region were condensed (the number in parentheses represents the number of strains included). Dotes represent the identical nucleotides in the compared sequences of virus genomes relative to the reference sequences (A: VARV strain India-1967, B: MPXV strain Zaire-96-I-16 and C: VZV strain Ellen); dashes represent the nucleotide deletions. The nucleotide positions in analyzed DNA segments are shown above the nucleotide sequences (positions according to the virus DNA: A, 161552–161671 bp according to the VARV India-1967 strain; B, 48362–48440 bp according to the MPXV Zaire-96-I-16 strain; C, 69295–69383 bp according to the VZV Ellen strain). A: UPPER, VARV_B12R_upper; PROBE, VARV_B12R_probe; LOWER, VARV_B12R_lower. B: UPPER, MPXV_F3L_upper; PROBE, MPXV_F3L_probe; LOWER, MPXV_F3L_lower. C: UPPER, VZV_ORF38_upper; PROBE, VZV_ORF38_probe; LOWER, VZV_ORF38_lower.