Figure 4.

Expression of serum-based ncRNA biomarker candidates in CSF in the BioMOx cohort. (A) No significant dysregulation of serum-based ncRNA biomarker candidates from Joilin et al. [7] were detected in CSF compared to the healthy controls. (B) No significant correlation in expression between CSF and serum in matched patient samples in the BioMOx cohort across all groups. Data from serum samples were collected as part of the study in Joilin et al. [7]. ALS-FP: fast-progressing ALS, ALS-SP: slow-progressing ALS; relative expression ± SD; normalised to geometric average of hsa-miR-9-5p and hsa-miR-501-3p; relative expression: one-way ANOVA with Tukey’s; correlation: Pearson’s correlation.