Table 2.

Clinical Trials for Cerebral Metastasis and Radiation Necrosis

Study	System	Patients (n)	Lesion	Pretreatment Lesion Volume	Treatment Time	Lesion Volume Ablated (%)	Imaging Modality	Complications
Sujijantarat et al.74	NeuroBlate	25	Radiation necrosis	0.3–12.6 cc	NR	65%	MRI	Seizure, hemiparesis, DVT
Ahluwalia et al.63	NeuroBlate	42	Metastasis, Radiation necrosis	0.4–38.6 cm3	NR	NR	MRI	Seizures, hemiparesis, cerebral edema
Carpentier et al.75	Visualase	6	Metastasis	9–25 mm diameter	30–225 sec	NR	MRI	None
Carpentier et al.76	Visualase	7	Metastasis	NR	30–180 sec	43%–50% contrast-enhancing tumor	MRI	Hemorrhage, cerebellar syndrome
Rennert et al.73	Neuroblate	34	Metastasis	NR	NR	NR	MRI	NR

Abbreviations: MRI, magnetic resonance imaging; NR, not recorded.