Table 2. Univariate analysis of factors associated with skeletal muscle mass index (SMI) in male.
All | Young-old (aged 60–74) | Old-old (aged 75≤) | ||||
---|---|---|---|---|---|---|
n = 152 | n = 90 | n = 62 | ||||
Variables | r | p-value | r | p-value | r | p-value |
Age | -0.363 | <0.001 | -0.228 | 0.031 | -0.317 | 0.012 |
BMI | 0.677 | <0.001 | 0.752 | <0.001 | 0.589 | <0.001 |
BFP | 0.033 | 0.685 | 0.203 | 0.055 | -0.015 | 0.909 |
HbA1c | -0.180 | 0.026 | -0.047 | 0.659 | -0.453 | <0.001 |
Total protein | -0.073 | 0.372 | -0.171 | 0.107 | 0.057 | 0.662 |
Albumin | 0.092 | 0.274 | -0.094 | 0.383 | 0.224 | 0.100 |
T-bilirubin | 0.088 | 0.280 | -0.096 | 0.371 | 0.318 | 0.012 |
ID-bilirubin | 0.133 | 0.111 | -0.093 | 0.389 | 0.383 | 0.004 |
Hypertension | 0.101 | 0.215 | 0.175 | 0.099 | 0.147 | 0.254 |
Hyperlipidemia | -0.105 | 0.200 | -0.108 | 0.309 | -0.087 | 0.504 |
CAD | -0.259 | 0.001 | -0.097 | 0.365 | -0.322 | 0.011 |
CVD | -0.062 | 0.449 | -0.029 | 0.787 | -0.008 | 0.950 |
Albuminuria | 0.003 | 0.975 | -0.057 | 0.605 | 0.153 | 0.240 |
Renal failure | 0.079 | 0.333 | -0.010 | 0.923 | 0.246 | 0.054 |
DDP4i | -0.006 | 0.940 | -0.060 | 0.573 | 0.020 | 0.875 |
SGLT2i | 0.140 | 0.085 | 0.148 | 0.165 | -0.031 | 0.814 |
SU | -0.144 | 0.076 | 0.009 | 0.936 | -0.278 | 0.029 |
Metformin | 0.108 | 0.187 | 0.130 | 0.222 | -0.036 | 0.783 |
GLP-1RA | -0.106 | 0.194 | -0.038 | 0.721 | -0.180 | 0.161 |
Insulin | -0.103 | 0.206 | -0.120 | 0.259 | -0.027 | 0.836 |
Spearman rank correlation test was performed to evaluate the correlation between skeletal muscle mass index
(SMI) and various variables.
Number of patients with missing data: Albumin, all n = 8, young-old n = 1, old-old n = 7; ID-Bil, all n = 8, young-old n = 1, old-old n = 7; Albuminuria, all n = 5, young-old n = 4, old-old n = 1.
Abbreviation: BMI, body mass index; SMI, skeletal muscle mass index; BFP, body fat percent; HbA1c, hemoglobin A1c; T-bilirubin, total bilirubin; ID-bilirubin, indirect bilirubin; CAD, cardiovascular disease; CVD, cerebrovascular disease; DPP4i, dipeptidyl peptidase-4 inhibitor; SGLT2i, sodium glucose co transporter-2 inhibitor; SU, sulfonylurea; GLP1-RA, glucagon-like peptide-1 receptor agonists.