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. 2022 Nov 2;17(11):e0276929. doi: 10.1371/journal.pone.0276929

Table 1. Demographic and clinical data of convalescents after liver transplantation.

OLT (n = 24)
Sex male (n;%) 13; 54.2
Time after transplantation in years median (min; max) 4.5 (1;28)
Underlying liver disease
Hereditary n; % 7; 29
Autoimmune liver disease n; % 6; 25
Viral hepatitis n; % 5; 21
Acute liver failure n; % 2; 8.3
Cryptic cirrhosis n; % 2; 8.3
Metabolic liver disease n; % 2; 8.3
Immunosuppression at diagnosis of COVID-19
Steroids yes n (%) 9; 27.5
Tacrolimus low n (%) 6; 25
high n (%) 15; 62.5
no Tac n (%) 3; 12.5
CsA yes n (%) 3; 12.5
CNI yes n (%) 24; 100
MMF yes n (%) 18; 75
MMF dose in mg/day median (min; max) 500 (0; 1500)
Everolimus yes n (%) 3; 12.5
Aza yes n (%) 1; 4.2
Aza dose in mg/day 50
Sirolimus yes n (%) 1; 4.2
IS score 1 1; 4.2
2 8; 33.3
3 6; 25
4 6; 25
5 2; 8
6 1; 4.2
Reduction immunosuppression during COVID-19 yes (n;%) 4; 16.6
Symptoms during infection (multiple answers possible)
None n; % 2; 13.3
Cough/dyspnea n; % 9; 60
Fatigue n; % 5; 30
Fever n; % 4; 26.7
Body aches n; % 3; 20
Headache n; % 2; 13.3
Score throat n; % 2; 13.3
Sweat n; % 1; 6.7
Sniffles n; % 1; 6.7
WHO clinical progression scale
1 7
2 14
3 1
4 2
Hospitalization during COVID-19 yes (n;%) 4; 16.6
1–2 months 3–4 months ≥ 5 months non-vacc. ≥ 5 months vacc.
n = 15 n = 16 n = 3 n = 14
Sex male (n;%) 9; 60 9; 56.3 2; 66.7 8; 57.1
Age median (min; max) 56 (25;68) 56 (22;72) 56 (20;68) 56 (32; 72)
Time after diagnosis in weeks median (min; max) 6 (3;8) 15 (9;20) 26 (25; 30) 29 (24;56)
Symptoms (multiple answers possible)
None n; % 3; 20 10; 62.5 3; 100 11; 78.6
Cough/dyspnea n; % 4; 26.7 3, 18.8 0; 0 1; 12.8
Fatigue n; % 6; 40 2; 12.5 0; 0 2; 14.3
Fever n; % 1; 6.7 0; 0 0; 0 0; 0
Body aches n; % 1; 6.7 0; 0 0; 0 0; 0
Headache n; % 1; 6.7 0; 0 0; 0 0; 0
Score throat n; % 3; 20 2; 12.5 0; 0 0; 0
Sweat n; % 0; 0 0; 0 0; 0 0; 0
Sniffles n; % 1; 6.7 0; 0 0; 0 0; 0
AST median (min; max) 25 (8;180) 26 (15;100) 20 (13;22) 26 (16;68)
ALT median (min; max) 28 (10;308) 25 (5;86) 15 (12;21) 22 (4;82)
GGT median (min; max) 32 (11;1353) 32 (5;487) 19 (18;86) 26 (7;584)
AP median (min; max) 104 (58;564) 92 (60;470) 99 (60;110) 98 (5;630)
Bili median (min; max) 9 (5;74) 13 (5;23) 6 (4;10) 12 (7;118)
IgG median (min; max) 10.37 (7.7; 22.35) 10.54 (6.02; 18.61) 10.95 (10.95; 10.95) 10.41 (9.5; 18.85)