Fig 7. Signal transduction under pertubations.

Parameters were altered between half (0.5 * k) and double (2.0 * k) their original values individually to determine which parameters prevent reliable transduction of the signal from receptor to gene expression under considered perturbations. The effect on the ISG induction was quantified by repeating the stochastic simulation 600 times and computing the relative change in IFIT and MxA molecules to the unpertubated system.