Table 1. The mean, median and 95% reference intervals of clinical chemistry parameters for healthy adults in Northeast Ethiopia.
| Parameters | Sex | Mean | Median | 95% RI | 95% RI | P-value | |
|---|---|---|---|---|---|---|---|
| 90% CI (lower limit) | 90% CI (upper limit) | ||||||
| ALT (U/L) | Combined | 25.2 | 23.0 | 11.2–48.0 | 7.0, 14.0 | 43.0, 55.0 | 0.002 |
| Males | 26.7 | 25.0 | 14.0–48.9 | 6.0, 15.0 | 43.0, 60.0 | ||
| Females | 23.8 | 21.0 | 7.9–48.0 | 6.0, 13.0 | 40.0, 53.0 | ||
| AST (U/L) | Combined | 36.8 | 33.0 | 16.0–60.0 | 15.0, 21.0 | 60.0, 63.0 | < 0.001 |
| Males | 39.6 | 38.0 | 18.9–63.0 | 16.0, 21.0 | 60.0, 69.0 | ||
| Females | 34.0 | 30.0 | 15.9–59.0 | 15.0, 16.0 | 54.0, 59.0 | ||
| ALP (U/L) | Combined | 196.2 | 195.0 | 53.0–342.3 | 49.0, 55.0 | 320.0, 346.0 | 0.009 |
| Males | 208.6 | 204.0 | 55.0–343.4 | 48.0, 105.0 | 330.0, 359.0 | ||
| Females | 183.9 | 182.5 | 50.0–326.3 | 45.0, 54.0 | 309.0, 345.0 | ||
| Total protein (g/dl) | Combined | 6.9 | 7.0 | 5.4–8.9 | 5.2, 5.5 | 8.9, 9.0 | 0.453 |
| Males | 6.9 | 6.8 | 5.5–8.1 | 5.2, 5.6 | 7.8, 8.7 | ||
| Females | 6.9 | 7.1 | 5.2–9.0 | 4.8, 5.4 | 8.9, 9.0 | ||
| Total bilirubin (mg/dl) | Combined | 0.53 | 0.40 | 0.10–1.23 | 0.10, 0.11 | 1.20, 1.30 | 0.500 |
| Males | 0.53 | 0.45 | 0.10–1.30 | 0.10, 0.11 | 1.20, 1.30 | ||
| Females | 0.53 | 0.40 | 0.10–1.20 | 0.10, 0.12 | 1.18, 1.22 | ||
| Glucose (mg/dl) | Combined | 94 | 94 | 60–125 | 60, 64 | 119, 130 | 0.999 |
| Males | 96 | 97 | 65–126 | 61, 69 | 124,130 | ||
| Females | 94 | 95 | 60–119 | 59, 61 | 116, 122 | ||
| Total cholesterol (mg/dl) | Combined | 159 | 160 | 69–213 | 69, 80 | 210, 217 | 0.042 |
| Males | 157 | 160 | 97–208 | 76, 100 | 204, 217 | ||
| Females | 161 | 171 | 69–216 | 61, 79 | 213, 227 | ||
| Triglycerides (mg/dl) | Combined | 136 | 140 | 46–207 | 36, 61 | 203, 232 | 0.029 |
| Males | 140 | 146 | 44–220 | 12, 60 | 203, 238 | ||
| Females | 132 | 133 | 46–207 | 36, 61 | 203, 236 | ||
| Creatinine (mg/dl) | Combined | 0.76 | 0.80 | 0.30–1.20 | 0.30, 0.40 | 1.20, 1.30 | 0.002 |
| Males | 0.81 | 0.80 | 0.40–1.30 | 0.40, 0.50 | 1.20, 1.30 | ||
| Females | 0.71 | 0.70 | 0.30–1.11 | 0.30, 0.40 | 1.10, 1.20 | ||
| Urea (mg/dl) | Combined | 26.3 | 25.5 | 9.5–46.3 | 6.0, 14.0 | 45.0, 48.0 | < 0.001 |
| Males | 28.4 | 28.0 | 13.0–47.1 | 6.0, 15.0 | 45.0, 48.0 | ||
| Females | 24.3 | 24.0 | 8.0–41.5 | 6.0, 10.0 | 36.1, 46.1 | ||
P-value: Mann–Whitney U test for males versus females; ALT: alanine aminotransferase; ALP: alkaline phosphatase; AST: aspartate aminotransferase; CI: confidence interval; mg/dl: milligram per deciliter; RI: reference interval; U/L: units per liter