Table 2. Comparison of clinical chemistry reference intervals obtained in this study with previous studies in Ethiopia and the values currently in use.

Parameters	Sex	Present study	Northwest Ethiopia (Gojjam) [19]	Amhara Regional State [15]	Southwest Ethiopia [20]	Currently in use
ALT (U/L)	C	11–48	6.0–43.0	5.0–39.0	11.0–54.0	0–42
	M	14–49	6.0–44.6	5.1–42.9	11.2–56.0
	F	7.9–48	3.0–30.0	4.3–37.0	10.1–54.0
AST (U/L)	C	16–60	9.0–38.0	11.0–46.0	12.0–59.0	0–37
	M	19–63	10.5–39.0	12.1–46.9	13.0–59.5
	F	16–59	6.0–32.1	10.0–43.8	12.0–59.9
ALP (U/L)	C	53–342	52.4–237.0	87.0–451.3	63.0–376.0	0–270
	M	55–343	55.3–237.2	77.2–475.8	55.8–362.9
	F	50–326	49.0–236.0	89.0–381.0	70.4–384.4
Total protein (g/dl)	C	5.4–8.9	5.3–8.6	5.7–9.6	4.4–11.6	5.3–8.7
	M	5.5–8.1	5.3–8.67	5.7–9.7	4.0–11.4
	F	5.2–9.0	5.32–8.60	5.6–9.5	4.6–11.7
Total bilirubin (mg/dl)	C	0.1–1.23	0.26–2.18	0.1–1.1	NA	0–1.2
	M	0.1–1.3	0.27–2.18	0.1–1.2	NA
	F	0.1–1.2	0.21–2.18	0.08–0.9	NA
Glucose (mg/dl)	C	60–125	NA	NA	NA	70–110
	M	65–126	NA	NA	NA
	F	60–119	NA	NA	NA
Total cholesterol (mg/dl)	C	69–213	NA	80.4–206.6	55.0–276.0	0–200
	M	97–208	NA	78.1–211.8	52.1–252.2
	F	69–216	NA	83.6–202.7	58.0–286.4
Triglycerides (mg/dl)	C	46–207	NA	36.0–215.6	41.0–264.0	0–165
	M	44–220	NA	36.0–221.9	41.3–275.8
	F	46–207	NA	35.3–201.5	41.0–261.2
Creatinine (mg/dl)	C	0.3–1.2	0.23–1.22	0.47–1.12	0.32–1.32	0.5–1.2
	M	0.4–1.3	0.2–1.29	0.48–1.13	0.3–1.4
	F	0.3–1.11	0.25–1.08	0.47–1.09	0.3–1.3
Urea (mg/dl)	C	9.5–46.3	NA	11.0–41.0	4.6–35.0	10–50
	M	13.0–47.1	NA	12.0–43.0	4.6–34.5
	F	8.0–41.5	NA	10.0–38.7	4.5–35.8

ALT: alanine aminotransferase; ALP: alkaline phosphatase; AST: aspartate aminotransferase; C: combined for both males and females; F: females; M: males; mg/dl: milligram per deciliter; NA: not available; U/L: units per liter