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. 2022 Aug 2;22(9):1267–1269. doi: 10.1016/S1473-3099(22)00513-8

Table.

Timeline of monkeypox virus DNA detection in plasma, urine, and semen samples with increasing days from symptom onset

Day 5 Day 6 Day 7 Day 8 Day 9 Day 10 Day 11 Day 13 Day 14 Day 15 Day 16 Day 17 Day 19
Plasma NA NA NA Positive (34·5) NA Negative NA Negative NA Negative Negative Negative Negative
Urine NA NA Negative NA Negative NA Negative Negative NA Negative NA NA Negative
Semen Positive (28·0) Positive (29·3) Positive (27·8) NA NA NA NA NA Positive (34·3) Positive (35·6) NA Positive (38·7) Positive (40·6)
Rash or skin lesion Positive Positive Positive Positive Positive Positive Positive Positive Positive Positive Positive Positive Negative

Quantification cycle values are indicated in brackets after positive results. The cutoff cycle threshold is 45, thresholds of 42 or higher are retested for confirmation. Negative indicates no detection of monkeypox virus DNA or absence of rash or skin lesions. Positive indicates detection of monkeypox virus DNA or presence of rash or skin lesions. NA=not available.