Table 3. Univariable and Multivariable Logistic Analysis for Factors Associated with Poor Functional Outcomes at 3 Months after Stroke.
| Univariable | Multivariable | ||||
|---|---|---|---|---|---|
| Odds ratio (95% CI) | p value | Odds ratio (95% CI) | p value | ||
| Demographic | |||||
| Age, yr | 1.07 (1.03–1.12) | 0.002 | 1.06 (1.00–1.12) | 0.038 | |
| Sex, male | 0.65 (0.25–1.70) | 0.383 | 0.59 (1.07–2.07) | 0.410 | |
| Comorbidities | |||||
| Hypertension | 2.54 (0.92–6.99) | 0.072 | |||
| Diabetes mellitus | 3.02 (0.95–9.54) | 0.061 | |||
| Dyslipidemia | 0.67 (0.24–1.84) | 0.435 | |||
| Coronary artery disease | 0.45 (0.13–1.53) | 0.199 | |||
| Atrial fibrillation | 2.87 (1.05–7.88) | 0.041 | 1.50 (0.37–6.04) | 0.569 | |
| Peripheral artery disease | 0.82 (0.05–13.64) | 0.890 | |||
| Previous stroke | 1.87 (0.57–6.14) | 0.304 | |||
| Active cancer | 5.65 (0.64–49.49) | 0.118 | |||
| Current smoker | 0.59 (0.12–2.84) | 0.508 | |||
| Laboratory findings | |||||
| Hemoglobin, g/dL | 0.84 (0.56–1.06) | 0.146 | |||
| Hematocrit, % | 1.00 (0.92–1.07) | 0.904 | |||
| WBC, 103/μL | 1.01 (0.86–1.20) | 0.868 | |||
| Platelet, 109/L | 1.00 (0.99–1.01) | 0.847 | |||
| ESR, mm/h | 1.01 (0.99–1.04) | 0.223 | |||
| CRP, mg/L | 0.99 (0.98–1.01) | 0.338 | |||
| Total cholesterol, mg/dL | 1.01 (0.99–1.02) | 0.358 | |||
| HDL-cholesterol, mg/dL | 1.00 (0.97–1.02) | 0.907 | |||
| LDL-cholesterol, mg/dL | 1.01 (0.99–1.02) | 0.295 | |||
| Triglyceride, mg/dL | 1.00 (1.00–1.00) | 0.701 | |||
| D-dimer, ng/mL | 1.00 (1.00–1.00) | 0.059 | |||
| Fibrinogen, mg/dL | 1.00 (0.99–1.06) | 0.211 | |||
| BUN, mg/dL | 1.07 (1.00–1.14) | 0.063 | |||
| Creatinine, mg/dL | 1.45 (0.32–6.63) | 0.630 | |||
| Albumin, mg/dL | 0.50 (0.15–1.67) | 0.260 | |||
| Glucose, mg/dL | 1.01 (1.00–1.03) | 0.045 | 1.02 (1.00–1.04) | 0.048 | |
| Stroke classification | |||||
| Cardioembolism | 1.52 (0.28–8.28) | 0.626 | |||
| Large artery atherosclerosis | Reference | Reference | |||
| Undetermined | 0.56 (0.08–3.86) | 0.552 | |||
| Intravenous tPA | 0.51 (0.18–1.42) | 0.196 | |||
| Initial NIHSS | 1.15 (1.06–1.26) | 0.001 | 1.12 (1.01–1.24) | 0.025 | |
| Recanalization outcome | |||||
| TICI 2b or 3 | 0.22 (0.02–1.97) | 0.176 | |||
| TICI 3 | 0.25 (0.00–0.72) | 0.011 | 0.20 (0.05–0.79) | 0.021 | |
| Onset-to recanalization time, min | 1.00 (1.00–1.00) | 0.752 | |||
| Thrombus composition, % | |||||
| Platelet | 1.01 (0.97–1.04) | 0.797 | |||
| Fibrinogen | 1.00 (0.95–1.04) | 0.917 | |||
| Erythrocyte | 1.00 (0.97–1.03) | 0.146 | |||
| Neutrophil | 1.05 (1.00–1.09) | 0.032 | 1.03 (0.97–1.10) | 0.267 | |
CI, confidence interval; WBC, white blood cell; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; BUN, blood urea nitrogen; tPA, tissue plasminogen activator; NIHSS, National Institute of Health Stroke Scale; TICI, thrombolysis in cerebral infarction.