TABLE 2.
LD50 values of S. typhimurium strainsa
Bacterial strain | Mutation | Mouse strain | LD50 (CFU) |
---|---|---|---|
12023 | BALB/c | <10 | |
SL1344 | BALB/c | <13 | |
12023 | C3H/HeN | 4.20 × 103 | |
P11D10 | ssaJ::mTn5 | BALB/c | 1.35 × 106 |
P11D10 | ssaJ::mTn5 | C3H/HeN | 6.27 × 105 |
SLD10 | ssaJ::mTn5 | BALB/c | 9.27 × 105 |
Groups of five female BALB/c or C3H/HeN mice were inoculated i.p. with 1:10 dilutions of bacteria suspended in physiological saline. The LD50 values were calculated after 28 days by the method of Reed and Muench (42).