TABLE 3.
Bacteria carrying plasmid pHSG422 in gentamicin-treated spleen cell suspensions at 16 h postinoculationa
| Strain | Total CFU (log10) | CFU/pHSG422 (log10) | Proportional distance (log10) | Approx. no. of generations |
|---|---|---|---|---|
| 12023 | ||||
| Gentamicin protected | 4.54 ± 0.09 | 3.21 ± 0.12* | 1.23 ± 0.33‡ | 4 |
| Gentamicin sensitive | 5.40 ± 0.12 | 3.55 ± 0.20* | 1.84 ± 0.18‡ | 5–6 |
| Total | 5.46 ± 0.11 | 3.74 ± 0.15** | 1.73 ± 0.14 | 5–6 |
| P11D10 | ||||
| Gentamicin protected | 4.18 ± 0.21 | 3.09 ± 0.14* | 1.09 ± 0.10† | 3 |
| Gentamicin sensitive | 4.66 ± 0.23 | 3.63 ± 0.12* | 1.05 ± 0.15† | 3 |
| Total | 4.79 ± 0.22 | 3.73 ± 0.11** | 1.06 ± 0.13 | 3 |
a
Each figure is the mean of 10 mice ± 1 SD. The proportional distance was calculated as the log10 total CFU − log10 plasmid bearing CFU for each mouse and the calculated mean of 10 mice. P values are for the null hypothesis that means are not statistically different and are as follows: ∗, P > 0.05; ∗∗, P > 0.5; †, P > 0.25; ‡, P < 0.001.