Table 4. HRs of Death in Patients with TS and Age-Matched Controls from 2007 to 2017.
| n | Event | Duration (person-years) | MR (per 1000 persons) | HR (95% CI) unadjusted | p value | HR (95% CI) adjusted* | p value | |||
|---|---|---|---|---|---|---|---|---|---|---|
| All cause of death | Control | 4305 | 13 | 22855.52 | 0.57 | 1 | 1 | |||
| TS | 1435 | 16 | 7571.16 | 2.11 | 3.72 (1.79–7.73) | <0.001 | 3.36 (1.59–7.10) | 0.002 | ||
| Death in TS by age | 0–19 | Control | 2910 | 3 | 14786.09 | 0.20 | 1 | 1 | ||
| TS | 970 | 3 | 4917.83 | 0.61 | 3.01 (0.61–14.89) | 0.178 | 3.07 (0.62–15.21) | 0.169 | ||
| 20–39 | Control | 1074 | 5 | 6372.98 | 0.78 | 1 | 1 | |||
| TS | 358 | 3 | 2115.72 | 1.42 | 1.81 (0.43–7.59) | 0.415 | 0.36 (0.05–2.63) | 0.312 | ||
| ≥40 | Control | 321 | 5 | 1696.45 | 2.95 | 1 | 1 | |||
| TS | 107 | 10 | 537.61 | 18.60 | 6.33 (2.16–18.52) | <0.001 | 6.51 (2.19–19.32) | <0.001 | ||
DM, diabetes mellitus; TS, Turner syndrome; MR, mortality rate; HR, hazard ratio; CI, confidence interval.
*Adjusted for residence, income, and DM.