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. 2022 Oct 26;2022:8275574. doi: 10.1155/2022/8275574

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Copyright © 2022 Jinlai Zhao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FXR overexpression inhibits malignant progression of colon cancer cells. (a) qRT-PCR confirmed the high expression of FXR in oe-FXR transfection group. (b and c) CCK-8 and colony formation assays were employed to analyze the effects of FXR overexpression on proliferation of HT-29 and SW480 cell lines. (d) The Transwell migration and invasion assays assessed the changes in motor capacity of colon cancer cells after overexpressing FXR. Each column is the average value of 3 independent experiments. (^∗ denotes P < 0.05).