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. 2022 Oct 26;2022:8275574. doi: 10.1155/2022/8275574

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Copyright © 2022 Jinlai Zhao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FXR activates DHRS9 to inhibit the malignant progression of colon cancer. (a) DHRS9 expression in transfected colon cancer cells detected by qRT-PCR. (b and c) Effect of FXR overexpression on HT-29 cell proliferation after DHRS9 expression blocking detected by CCK-8 and colony formation assays. (d and e) Changes in motor capacity of FXR overexpressed colon cancer cells after DHRS9 expression blocking assessed by Transwell migration and invasion assays. Each column is the average value of 3 independent experiments. (^∗ denotes P < 0.05).