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Serum Klotho level is negatively associated with calcification of aorta in clinical experiments. (a) The serum Klotho level is negatively associated with Agatston scores of aorta through Spearman rank analysis (n = 27). (b) the Agatston score in the low Klotho group is markedly higher than that in the Klotho group as determined by the Mann–Whitney U test (n = 27).
