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Effect and potential mechanism of ATF3 on T2DOP. Sixty SD rats were divided into four groups (n = 15). (a) Determination of iron ion, MDA, and GSH in serum. (b) IHC for GPX4, ATF3, and SLC7A11 in four groups of rats. Scale bar = 100 μm. ∗P < 0.05 vs. Ctrl and #P < 0.05 vs. T2DOP.
